• Anne Godier and Sophie Susen.
• Department of Anesthesia and Critical Care, Hôtel-Dieu and Cochin Hospitals, Paris Descartes University, Paris, France. anne.godier@htd.aphp.fr
• Curr Opin Anaesthesiol. 2012 Apr 1;25(2):242-7.

Purpose Of ReviewThe scope of this review is to describe what is known about blood product ratios and their effects on acute trauma coagulopathy. Assessing how ratios matter to trauma patients is important to improve massive transfusion strategies.Recent FindingsA growing body of evidence supports that high ratios of fresh frozen plasma and platelets to red blood cells improve survival of the massively bleeding traumatized patient. Acting quickly is also critical. Reducing transfusion delay can be achieved through massive transfusion protocol implementations, which incorporate local agreements with blood banks and 'trauma packs' in organized trauma systems. Thawed plasma and freeze-dried plasma allow immediate delivery of plasma.SummaryFresh frozen plasma/platelet/red blood cell ratios matter to define the content of packs immediately available within the golden hour to the right, accurately screened trauma patients. Research is needed in developing novel transfusion approaches for massively bleeding patients.

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