• Epilepsia · May 2013

    Review

    Animal and human data: where are our concepts for drug-resistant epilepsy going?

    • Heidrun Potschka.
    • Institute of Pharmacology, Toxicology, and Pharmacy, Ludwig-Maximilians-University, Munich, Germany. potschka@pharmtox.vetmed.uni-muenchen.de
    • Epilepsia. 2013 May 1; 54 Suppl 2: 29-32.

    AbstractDrug-resistant epilepsy remains a challenge in the therapeutic management of patients with epilepsy. Identification of factors contributing to drug resistance might render a basis for the development of novel therapeutic approaches, for the reorganization of screening programs in drug development, and for the design of personalized treatment concepts. Therefore, experimental and clinical studies need to link efforts and collaborate in order to elucidate drug-resistance mechanisms, to define the relative clinical relevance of selected mechanisms, and to develop and validate novel therapeutic concepts in overcoming resistance.Wiley Periodicals, Inc. © 2013 International League Against Epilepsy.

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