• Clin. Infect. Dis. · Sep 2005

    Nebulized colistin in the treatment of pneumonia due to multidrug-resistant Acinetobacter baumannii and Pseudomonas aeruginosa.

    • Andrea L H Kwa, ChinSiew Loh, Jenny G H Low, Asok Kurup, and Vincent H Tam.
    • Division of Infectious Diseases, Department of Pharmacy, Singapore General Hospital, Singapore. gpaklh@sgh.com.sg
    • Clin. Infect. Dis. 2005 Sep 1; 41 (5): 754-7.

    AbstractTwenty-one patients with multidrug-resistant (MDR) Acinetobacter baumannii and Pseudomonas aeruginosa pneumonia were treated with nebulized polymyxin E (colistin). Overall clinical and microbiological response rates were 57.1% and 85.7%, respectively. Nebulized colistin may be reasonably efficacious and safe for treatment of MDR pneumonia. Its role in therapy warrants further investigation in comparative studies.

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