• Keijiro Hori, Atsuyoshi Osada, Tsukasa Isago, and Hiroyuki Sakurai.
• Department of Plastic and Reconstructive Surgery, Tokyo Women's Medical University Medical Center East, 2-1-10, Nishiogu, Arakawa-ku, Tokyo 116-0011, Japan. Electronic address: hori.keijiro@twmu.ac.jp.
• Burns. 2017 Jun 1; 43 (4): 846-851.

AbstractVarious kinds of synthetic dermal substitutes are produced and used in clinical application and contribute to wound bed preparation for subsequent skin grafting. Although their appearance and outcomes are different, the criteria for the selection of proper synthetic dermal substitutes is not well defined yet. In this study, we focused on the contraction of dermal substitutes and compared the morphological differences in scaffolds. A marked contraction was observed with Pelnac® compared to Integra® and Terudermis® in vitro. We also showed that the pore size of Pelnac® was smaller than that of Integra® and Terudermis®. The shape of the pore was oval in Pelnac®, whereas those in Integra® and Terudermis® were more circular. Differences in the morphological structure may have affected the contraction of the synthetic dermal substitutes.Copyright © 2016 Elsevier Ltd and ISBI. All rights reserved.

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