Perioperative use of β-blockers in cardiac and noncardiac

JAMA · May 2015

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Perioperative use of β-blockers in cardiac and noncardiac surgery.

Are β-blockers associated with lower rates of mortality and morbidity after cardiac or noncardiac surgery? ⋯ In cardiac surgery, β-blockers are associated with a lower incidence of supraventricular tachycardias (SVTs) and ventricular arrhythmias. In noncardiac surgery, β-blockers are associated with a possible increase in mortality and strokes, a lower incidence of acute myocardial infarctions (AMIs) and SVTs, and an increase in bradycardia and hypotension. If tolerated, long-term β-blocker treatment should be continued perioperatively, whereas the decision to start a β-blocker should be individualized, weighing risks and benefits.

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- Hermann Blessberger, Juergen Kammler, and Clemens Steinwender.
- Department of Internal Medicine 1-Cardiology, Linz General Hospital, Johannes Kepler University Linz School of Medicine, Austria.
- JAMA. 2015 May 26;313(20):2070-1.
Clinical QuestionAre β-blockers associated with lower rates of mortality and morbidity after cardiac or noncardiac surgery?Bottom LineIn cardiac surgery, β-blockers are associated with a lower incidence of supraventricular tachycardias (SVTs) and ventricular arrhythmias. In noncardiac surgery, β-blockers are associated with a possible increase in mortality and strokes, a lower incidence of acute myocardial infarctions (AMIs) and SVTs, and an increase in bradycardia and hypotension. If tolerated, long-term β-blocker treatment should be continued perioperatively, whereas the decision to start a β-blocker should be individualized, weighing risks and benefits.

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Perioperative use of β-blockers in cardiac and noncardiac surgery.

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