• World Neurosurg · Feb 2017

    Review

    A review of stem cell therapy for spinal cord injury: large animal models and the frontier in humans.

    • Brandon C Gabel, Erik I Curtis, Martin Marsala, and Joseph D Ciacci.
    • Department of Neurosurgery, University of California, San Diego, San Diego, California, USA. Electronic address: bgabel@ucsd.edu.
    • World Neurosurg. 2017 Feb 1; 98: 438-443.

    ObjectiveTo review the literature of spinal cord injury and stem cell therapy for large animal models and incorporate those results into an understanding of stem cell therapy for human cord injury.MethodsReview of the literature.ResultsEleven canine studies were identified and 3 sub-human primate studies were identified showing variable results.ConclusionsStem cell therapy is a promising therapeutic option for patients with spinal cord injury; however, the technology has many un-answered questions and further research is needed.Copyright © 2016 Elsevier Inc. All rights reserved.

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