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Journal of anesthesia · Apr 2017
Prospective cohort study assessing chronic pain in patients following minor surgery for breast cancer.
- Régis Fuzier, Floriane Puel, Philippe Izard, Agnès Sommet, and Sébastien Pierre.
- Department of Anesthesiology, Institut Claudius Regaud. University Institute of Cancer Toulouse Oncopole, 1 Avenue Irène Joliot-Curie, 31059, Toulouse Cedex, France. fuzier.r@gmail.com.
- J Anesth. 2017 Apr 1; 31 (2): 246-254.
PurposePain after tumorectomy and sentinel lymph node dissection is poorly reported in the literature. We carried out a prospective survey aimed at assessing pain three months after such minor surgery for breast cancer.MethodsThe study was approved by the local ethics committee. Most surgeries followed a standard protocol involving general anesthesia with no regional analgesia technique, laryngeal mask, sufentanil and propofol for induction, and multimodal analgesia during the postoperative period. Three months after the surgery, a questionnaire was sent to the patients with a pre-stamped envelope for return. The questions probed responses required to calculate a Brief Pain Inventory score and modified neuropathic pain score (DN3).ResultsOver a 5-month period, 150 patients (aged 60 (11) years, body mass index of 25 (6) kg/m(2)) were included in the final analysis. In the recovery room, 43% of patients required morphine at a mean dose of 5.2 (1.8) mg. Three months post surgery, 60 patients (40%) reported persistent pain for which 62% took analgesic drugs. We found no risk factor associated with this persistent pain among our studied population. Neuropathic pain was noted in 61% of patients who reported persistent pain primarily associated with periareolar incision.ConclusionsPain persisted up to three months after minor surgery for breast cancer in 40% of patients with mostly a neuropathic component (61%).
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