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Am. J. Trop. Med. Hyg. · Oct 2007
Case ReportsTwo cases of Plasmodium vivax Malaria with the clinical picture resembling toxic shock.
- Joon Young Song, Cheong Won Park, You Mee Jo, Jeong Yun Kim, Jeong Hyun Kim, Hyo Joong Yoon, Chi Hoon Kim, Chae Seung Lim, Hee Jin Cheong, and Woo Joo Kim.
- Department of Internal Medicine, Korea University, Seoul, Republic of Korea.
- Am. J. Trop. Med. Hyg. 2007 Oct 1; 77 (4): 609-11.
AbstractFatal complications of Plasmodium falciparum malaria have been reported. However, complicated P. vivax malaria is rare. We observed two unusual cases of P. vivax malaria who presented with clinical pictures of toxic shock. Both showed disseminated intravascular coagulation with marked thrombocytopenia, oliguric renal failure, and pulmonary edema. Examination of initial blood smears showed a P. vivax parasitemia of 2,352/microL and 12,376/microL, respectively. The patients were treated with hydroxychloroquine and primaquine without an antibacterial agent. These cases emphasize the importance of considering the possibility of P. vivax malarial infection in patients with a clinical picture resembling toxic shock if they have a travel history to malaria-endemic areas.
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