• Critical care clinics · Jan 2017

    Review

    Optimal Fluid Therapy for Traumatic Hemorrhagic Shock.

    • Ronald Chang and John B Holcomb.
    • Center for Translational Injury Research, University of Texas Health Science Center, 6410 Fannin Street, Suite 1100, Houston, TX 77030, USA. Electronic address: ronald.chang@uth.tmc.edu.
    • Crit Care Clin. 2017 Jan 1; 33 (1): 15-36.

    AbstractThe resuscitation of traumatic hemorrhagic shock has undergone a paradigm shift in the last 20 years with the advent of damage control resuscitation (DCR). Major principles of DCR include minimization of crystalloid, permissive hypotension, transfusion of a balanced ratio of blood products, and goal-directed correction of coagulopathy. In particular, plasma has replaced crystalloid as the primary means for volume expansion for traumatic hemorrhagic shock. Predicting which patient will require DCR by prompt and accurate activation of a massive transfusion protocol, however, remains a challenge.Copyright © 2016 Elsevier Inc. All rights reserved.

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