• Emerg. Med. Clin. North Am. · Feb 2017

    Review

    Vasopressors and Inotropes in Sepsis.

    • Leeanne Stratton, David A Berlin, and John E Arbo.
    • Division of Emergency Medicine, New York Presbyterian Hospital/Weill Cornell Medical Center, New York, NY, USA.
    • Emerg. Med. Clin. North Am. 2017 Feb 1; 35 (1): 75-91.

    AbstractVasopressor and inotropes are beneficial in shock states. Norepinephrine is considered the first-line vasopressor for patients with sepsis-associated hypotension. Dobutamine is considered the first-line inotrope in sepsis, and should be considered for patients with evidence of myocardial dysfunction or ongoing signs of hypoperfusion. Vasopressor and inotrope therapy has complex effects that are often difficult to predict; emergency providers should consider the physiology and clinical trial data. It is essential to continually reevaluate the patient to determine if the selected treatment is having the intended result.Copyright © 2016 Elsevier Inc. All rights reserved.

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