• JAMA · Jun 2015

    Comment

    Nonsteroidal anti-inflammatory drugs for treatment of acute gout.

    • Caroline M P G van Durme, Mihir D Wechalekar, and Robert B M Landewé.
    • Department of Internal Medicine, Maastricht University Medical Center, the Netherlands2Centre Hospitalier Chrétien, Liège, Belgium.
    • JAMA. 2015 Jun 9;313(22):2276-7.

    Clinical QuestionAre nonsteroidal anti-inflammatory drugs (NSAIDs) associated with better outcomes than cyclooxygenase inhibitors, glucocorticoids, IL-1 inhibitors or placebo in the treatment of acute gout?Bottom LineNSAIDs are not significantly associated with a difference in pain reduction compared with cyclooxygenase inhibitors and glucocorticoids for treating acute gout. However, NSAIDs are associated with higher rates of adverse events and higher rates of withdrawal due to adverse events compared with cyclooxygenase inhibitors.

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