• Br J Anaesth · Dec 2016

    Review

    Perioperative goal-directed haemodynamic therapy based on flow parameters: a concept in evolution.

    • L Meng and P M Heerdt.
    • Department of Anesthesiology, Yale University School of Medicine, 330 Cedar St., PO Box 208051, New Haven, CT 06520, USA.
    • Br J Anaesth. 2016 Dec 1; 117 (suppl 3): iii3-iii17.

    AbstractHaemodynamic management incorporating direct or surrogate stroke volume monitoring has experienced a rapid evolution, because of emergence of the "goal-directed therapy" concept and technological developments aimed at providing a parameter leading to the goal. Nonetheless, consensus on both definitions of the ideal "goal" and strategies for achieving it remain elusive. For this review, we first consider basic physiological and patient monitoring factors relevant to the concept of "fluid responsiveness", and then focus upon randomized controlled trials and meta-analyses involving goal-directed haemodynamic therapy based on various flow parameters. Finally, we discuss the current status of noninvasive methods for monitoring fluid responsiveness.© The Author 2016. Published by Oxford University Press on behalf of the British Journal of Anaesthesia. All rights reserved. For Permissions, please email: journals.permissions@oup.com.

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