• L Chen and Y D Gu.
• Hand Surgery Department, Hua-Shan Hospital, Shanghai Medical University, Shanghai, 200040 China. lchenhkq@online.sh.cn
• Hand Surg. 2001 Jul 1; 6 (1): 37-45.

AbstractRat models with different division of nerve roots of the brachial plexus were designed to assess whether single or two nerve roots of the contralateral normal brachial plexus can be divided as donor nerves in treatment of brachial plexus root avulsion. Two hundred and fifty-two SD rats were randomly divided into 13 groups, i.e. five groups with single nerve root division, seven groups with two nerve roots division, and one group with three nerve roots division. Post-operative evaluation by electroneurophysiology and muscular histology was performed at two weeks and two months. Results showed that in groups with single nerve root division, the experimental limb function did not show an apparent damage; in groups with non-neighbouring two nerve roots cutting, it did show a harmful repercussions on the limb at two weeks, but most of them recovered to normal at two months; in groups with neighbouring two nerve roots division and with non-neighbouring three nerve root cutting, the limb function showed a persistent damage. In conclusion, division of nerve root alone or even non- neighbouring two nerve roots of the brachial plexus did not affect the forelimb function of the rat permanently.

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