• Thomas W L Scheeren and Bernd Saugel.
• Department of Anesthesiology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands. t.w.l.scheeren@umcg.nl.
• J Clin Monit Comput. 2017 Apr 1; 31 (2): 241-246.

AbstractIn the perioperative and critical care setting, monitoring of cerebral oxygenation (ScO2) and cerebral autoregulation enjoy increasing popularity in recent years, particularly in patients undergoing cardiac surgery. Monitoring ScO2 is based on near infrared spectroscopy, and attempts to early detect cerebral hypoperfusion and thereby prevent cerebral dysfunction and postoperative neurologic complications. Autoregulation of cerebral blood flow provides a steady flow of blood towards the brain despite variations in mean arterial blood pressure (MAP) and cerebral perfusion pressure, and is effective in a MAP range between approximately 50-150 mmHg. This range of intact autoregulation may, however, vary considerably between individuals, and shifts to higher thresholds have been observed in elderly and hypertensive patients. As a consequence, intraoperative hypotension will be poorly tolerated, and might cause ischemic events and postoperative neurological complications. This article summarizes research investigating technologies for the assessment of ScO2 and cerebral autoregulation published in the Journal of Clinical Monitoring and Computing in 2016.

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