• Blood purification · Jan 2012

    Review

    Acid-base and electrolyte abnormalities during renal support for acute kidney injury: recognition and management.

    • Rolando Claure-Del Granado, Rolando Claure, and Josée Bouchard.
    • Universidad del Valle, Cochabamba, Bolivia.
    • Blood Purif. 2012 Jan 1; 34 (2): 186-93.

    AbstractAcute kidney injury (AKI) is associated with electrolyte and acid-base disturbances such as hyperkalemia, metabolic acidosis, hypocalcemia and hyperphosphatemia. The initiation of dialysis in AKI can efficiently treat these complications. The choice of dialysis modality can be made based on their operational characteristics to tailor the therapy according to the clinical scenario. Each dialysis modality can also trigger significant electrolyte and acid-base disorders, such as hypokalemia, hypophosphatemia and metabolic alkalosis, which may direct changes in fluid delivery and composition. Continuous techniques may be particularly useful in these situations as they allow more time for correction and to maintain balance. This review provides an overview of the electrolyte and acid-base disturbances occurring in AKI and after the initiation of dialysis and discusses therapeutic options in this setting.Copyright © 2012 S. Karger AG, Basel.

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