• J Emerg Med · Apr 2017

    Case Reports

    Cecal Perforation Associated with Clostridium difficile Infection: A Case Report.

    • Sarah Kyuragi Luthe and Ryota Sato.
    • Department of Anesthesia, Urasoe General Hospital, Okinawa, Japan.
    • J Emerg Med. 2017 Apr 1; 52 (4): 554-556.

    BackgroundVarious complications are reported with Clostridium difficile infection (CDI), including fulminant CDI. Fulminant CDI is an underappreciated life-threatening condition associated with complications such as toxic megacolon and bowel perforation.Case ReportA 79-year-old woman presented to the Emergency Department with altered mental status. She was admitted and conservatively treated for a left thalamic hemorrhage. While hospitalized, she developed watery diarrhea due to Clostridium difficile. Although metronidazole was initiated, she developed altered mental status and septic shock. Abdominal x-ray study and computed tomography revealed a significantly dilatated colon and a massive pneumoperitoneum. She underwent subtotal colectomy with a 14-day course of intravenous meropenem. WHY SHOULD AN EMERGENCY PHYSICIAN BE AWARE OF THIS?: This case suggests that we must be aware of the complications that CDI may present and adequately consider surgical management because early diagnosis and surgical treatment is critical to reduce the mortality of fulminant CDI.Copyright © 2016 Elsevier Inc. All rights reserved.

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