• Critical care clinics · Apr 2000

    Review

    Metabolic derangements in sepsis and septic shock.

    • B A Mizock.
    • Department of Medicine, Cook County Hospital, Chicago, Illinois, USA.
    • Crit Care Clin. 2000 Apr 1; 16 (2): 319-36, vii.

    AbstractThis article examines the spectrum of metabolic alterations in sepsis and septic shock. The clinical manifestations, neuroendocrine control, and bioenergetics of the "ebb" and "flow" phases of sepsis are reviewed. Characteristic alterations in carbohydrate, fat, and protein metabolism induced by sepsis are outlined. Finally, the implications of these metabolic alterations for the nutritional support of patients with sepsis are discussed.

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