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- Kerry Woolnough and Andrew J Wardlaw.
- Department of Infection Immunity and Inflammation, Institute for Lung Health, University of Leicester, Groby Road, Leicester LE3 9QP, UK; Department of Respiratory Medicine and Allergy, University Hospitals of Leicester NHS Trust, Groby Road, Leicester LE3 9QP, UK.
- Immunol Allergy Clin North Am. 2015 Aug 1; 35 (3): 477-92.
AbstractLung disease associated with marked peripheral blood eosinophilia is unusual and nearly always clinically significant. Once recognized, it is generally easy to manage, albeit with long-term systemic corticosteroids. A failure to respond to oral steroids in the context of good compliance suggests a malignant cause for the eosinophilia. An important development is the introduction of antieosinophil therapies, particularly those directed against the interleukin 5 pathway, which is hoped to provide benefit in the full spectrum of eosinophilic lung disease as well as asthma, reducing the burden of side effects and resultant comorbidities.Copyright © 2015 Elsevier Inc. All rights reserved.
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