• Br J Surg · Mar 2017

    Practice Guideline

    European Society of Endocrine Surgeons (ESES) and European Network for the Study of Adrenal Tumours (ENSAT) recommendations for the surgical management of adrenocortical carcinoma.

    • S Gaujoux, R Mihai, and joint working group of ESES and ENSAT.
    • Department of Digestive and Endocrine Surgery, Cochin Hospital, Assistance Publique - Hôpitaux de Paris (APHP), Paris, France.
    • Br J Surg. 2017 Mar 1; 104 (4): 358-376.

    BackgroundRadical surgery provides the best chance of cure for adrenocortical carcinoma (ACC), but perioperative surgical care for these patients is yet to be standardized.MethodsA working group appointed jointly by ENSAT and ESES used Delphi methodology to produce evidence-based recommendations for the perioperative surgical care of patients with ACC. Papers were retrieved from electronic databases. Evidence and recommendations were classified according to the Grading of Recommendations, Assessment, Development and Evaluation (GRADE) system, and were discussed until consensus was reached within the group.ResultsTwenty-five recommendations for the perioperative surgical care of patients with ACC were formulated. The quality of evidence is low owing to the rarity of the disease and the lack of prospective surgical trials. Multi-institutional prospective cohort studies and prospective RCTs are urgently needed and should be strongly encouraged.ConclusionThe present evidence-based recommendations provide comprehensive advice on the optimal perioperative care for patients undergoing surgery for ACC.© 2017 BJS Society Ltd Published by John Wiley & Sons Ltd.

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