• Arq Neuropsiquiatr · Sep 1996

    Case Reports

    [Cerebrospinal fluid in the diagnosis of cerebro-meningeal metastasis from malignant melanoma arising from giant congenital melanocytic nevus: case report].

    • J A Rolim, O G Barsottini, G F Prado, F Nakandakare, M L Reis, and J B Reis-Filho.
    • Escola Paulista de Medicina (EPM) da Universidade Federal de São Paulo(UNIFESP), Brasil.
    • Arq Neuropsiquiatr. 1996 Sep 1; 54 (3): 479-83.

    AbstractWe describe the case of a 28-year-old man with a giant congenital melanocytic nevus (GCMN) with malignant transformation to melanoma and metastasis on the central nervous system (CNS). We also make a summary of the pathological features from both lesions (GCMN and Melanoma), the occurrence of malignancy of GCMN, the organs more frequently involved with metastatic melanoma--with emphasis to involvement of CNS--just as the factors that cause malignant transformation of GCMN; the methods to diagnose metastases in CNS--emphasizing the importance of cerebrospinal fluid--and some therapeutical modalities for the metastatic melanoma in CNS.

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