• Pediatric emergency care · Apr 2019

    Case Reports

    The Presentation of a Fussy Infant With Bruising: Late-Onset Vitamin K Deficiency Bleeding.

    • Katherine Wolpert, Matthew Szadkowski, Michael Miescier, and Hilary A Hewes.
    • From the Department of Pediatrics and.
    • Pediatr Emerg Care. 2019 Apr 1; 35 (4): e70-e71.

    AbstractVitamin K plays an integral role in the clotting cascade. Deficiency, specifically in vulnerable neonates with insufficient stores, can lead to spontaneous bleeding and devastating effects. In this case, we report a young infant with late-onset vitamin K deficiency bleeding who did not receive vitamin K prophylaxis after birth. Initially presenting with bruising and fussiness, the patient was later found to have intracerebral hemorrhage with midline shift and uncal herniation. The infant was not a surgical candidate and died shortly thereafter. Laboratory studies confirmed the diagnosis of late-onset vitamin K deficiency bleeding as the cause of hemorrhage and death.

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