• Alexey N Shkarubo, Alexander A Kuleshov, Ilia V Chernov, and Marchel S Vetrile.
• Department of Neurooncology, the N.N. Burdenko Neurosurgery Institute, Moscow, Russia.
• World Neurosurg. 2017 Jun 1; 102: 181-190.

ObjectivePresentation of clinical cases involving successful anterior stabilization of the C1-C2 segment in patients with invaginated C2 odontoid process and Chiari malformation type I.MethodsClinical case description.ResultsTwo patients with C2 odontoid processes invagination and Chiari malformation type I were surgically treated using the transoral approach. In both cases, anterior decompression of the upper cervical region was performed, followed by anterior stabilization of the C1-C2 segment. In 1 of the cases, this procedure was performed after posterior decompression, which led to transient regression of neurologic symptoms. In both cases, custom-made cervical plates were used for anterior stabilization of the C1-C2 segment. During the follow-up period of more than 2 years, a persistent regression of both the neurologic symptoms and Chiari malformation was observed.ConclusionsAnterior decompression followed by anterior stabilization of the C1-C2 segment is a novel and promising approach to treating Chiari malformation type I in association with C2 odontoid process invagination.Copyright © 2017 Elsevier Inc. All rights reserved.

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