• Critical care clinics · Apr 2017

    Review

    Renal Replacement Therapy in Acute Kidney Injury: Controversies and Consensus.

    • Michael Heung and Lenar Yessayan.
    • Division of Nephrology, Department of Medicine, University of Michigan, 1500 East Medical Center Drive, SPC 5364, Ann Arbor, MI 48109-5364, USA. Electronic address: mheung@umich.edu.
    • Crit Care Clin. 2017 Apr 1; 33 (2): 365-378.

    AbstractAcute kidney injury (AKI) is a common complication among critically ill patents, and 5% of intensive care unit (ICU) patients require initiation of renal replacement therapy (RRT). In recent years, clinical trials have provided evidence-based guidance for some important aspects of RRT management in patients with AKI, such as dialysis dosing and approaches to anticoagulation in patients undergoing continuous RRT. However, there remain many areas of uncertainty, and delivery of RRT in the ICU requires clinical judgment, flexibility, and an understanding of dialysis principles. This article reviews the components of RRT prescription and provides an update on best practices.Copyright © 2016 Elsevier Inc. All rights reserved.

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