• Christian P Subbe, Bernd Duller, and Rinaldo Bellomo.
• Respiratory & Critical Care Medicine, Bangor University & Ysbyty Gwynedd, Bangor, LL57 2PW, Wales, UK. csubbe@hotmail.com.
• Crit Care. 2017 Mar 14; 21 (1): 52.

BackgroundDelayed response to clinical deterioration of ward patients is common.MethodsWe performed a prospective before-and-after study in all patients admitted to two clinical ward areas in a district general hospital in the UK. We examined the effect on clinical outcomes of deploying an electronic automated advisory vital signs monitoring and notification system, which relayed abnormal vital signs to a rapid response team (RRT).ResultsWe studied 2139 patients before (control) and 2263 after the intervention. During the intervention the number of RRT notifications increased from 405 to 524 (p = 0.001) with more notifications triggering fluid therapy, bronchodilators and antibiotics. Moreover, despite an increase in the number of patients with "do not attempt resuscitation" orders (from 99 to 135; p = 0.047), mortality decreased from 173 to 147 (p = 0.042) patients and cardiac arrests decreased from 14 to 2 events (p = 0.002). Finally, the severity of illness in patients admitted to the ICU was reduced (mean Acute Physiology and Chronic Health Evaluation II score: 26 (SD 9) vs. 18 (SD 8)), as was their mortality (from 45% to 24%; p = 0.04).ConclusionsDeployment of an electronic automated advisory vital signs monitoring and notification system to signal clinical deterioration in ward patients was associated with significant improvements in key patient-centered clinical outcomes.Trial RegistrationClinicalTrials.gov, NCT01692847 . Registered on 21 September 2012.

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