• World Neurosurg · May 2017

    Case Reports

    Idiopathic intracranial hypertension in monozygotic female twins: Intracranial pressure dynamics and treatment outcome.

    • Manolis Polemikos, Hans E Heissler, Elvis J Hermann, and Joachim K Krauss.
    • Department of Neurosurgery, Hannover Medical School, Hannover, Germany. Electronic address: polemikos_manolis@hotmail.com.
    • World Neurosurg. 2017 May 1; 101: 814.e11-814.e14.

    BackgroundFamilial cases of idiopathic intracranial hypertension (IIH) are exceedingly rare, and its occurrence in monozygotic twins has not been reported previously.Case DescriptionWe report monozygotic female twins who developed IIH, one at age 25 years and the other at age 28 years. Continuous intracranial pressure (ICP) monitoring confirmed elevated ICP as measured initially by lumbar puncture. In both cases, successful treatment with resolution of papilledema and symptoms relief was achieved after ventriculoperitoneal shunting.ConclusionsThis report documents the first case of IIH in monozygotic twins and the associated changes in ICP dynamics. Interestingly, almost equivalent alterations in ICP dynamics were found in the 2 patients.Copyright © 2017 Elsevier Inc. All rights reserved.

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