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- Bruce Hamilton, Peter Fowler, Howard Galloway, and Nebojsa Popovic.
- Aspetar Qatar Orthopaedic and Sports Medicine Hospital, Doha, Qatar. bruce.hamilton@aspetar.com
- Acta Orthop Belg. 2008 Dec 1; 74 (6): 860-4.
AbstractNicolau Syndrome (also known as Embolia cutis medicamentosa and livedo-like dermatitis) is a rare but severe localized adverse drug reaction to a range of intra-muscular preparations. It manifests as acute pain, cutaneous, subcutaneous and intra-muscular inflammation and necrosis immediately following an injection, with potentially devastating sequelae. We describe the syndrome in a 21-year-old national level race walk athlete following an intramuscular diclofenac injection.
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