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Paediatric anaesthesia · Jul 2017
Case ReportsAnaphylactic reaction to tranexamic acid in an adolescent undergoing posterior spinal fusion.
- Jennifer Chiem, Iskra Ivanova, Andrew Parker, Walter Krengel, and Nathalia Jimenez.
- Department of Anesthesiology and Pain Medicine, Seattle Children's Hospital, University of Washington, Seattle, WA, USA.
- Paediatr Anaesth. 2017 Jul 1; 27 (7): 774-775.
AbstractTranexamic acid is an anti-fibrinolytic agent frequently used in pediatric surgery. Common side effects include nausea, flushing, and headache, but in rare instances, it may produce anaphylaxis; with only one previously reported case in a 72-year-old man. We report a case of a delayed anaphylactic reaction in a pediatric patient undergoing posterior spine fusion; and discuss the intraoperative management of the acute event, immunologic confirmation, and subsequent anesthetic approach.© 2017 John Wiley & Sons Ltd.
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