• Burns · Mar 2017

    The ability of selected plant essential oils to enhance the action of recommended antibiotics against pathogenic wound bacteria.

    • Monika Sienkiewicz, Monika Łysakowska, Edward Kowalczyk, Grażyna Szymańska, Ewa Kochan, Jolanta Krukowska, Jurek Olszewski, and Hanna Zielińska-Bliźniewska.
    • Department of Allergology and Respiratory Rehabilitation, 2nd Chair of Otolaryngology, Medical University of Lodz, Poland. Electronic address: monika.sienkiewicz@umed.lodz.pl.
    • Burns. 2017 Mar 1; 43 (2): 310-317.

    AbstractThe aim of this work was to characterize the ability of essential oils to support antibiotics against pathogenic bacteria in wounds. Gram-positive and Gram-negative bacteria obtained from wound infections were identified according to standard microbiological methods. Essential oils were analysed by GC-FID-MS. The susceptibility of bacteria to antibiotics, essential oils and their combination was assessed using the disc-diffusion method. The Minimal Inhibitory Concentration and Minimum Bactericidal Concentration of the essential oils were established by the micro-dilution broth method. Although cinnamon, clove, thyme and lavender essential oils were found to have the greatest antibacterial activity when used alone, the greatest additive and synergistic effects against pathogenic wound bacteria in combination with recommended antibiotics were demonstrated by basil, clary sage and rosemary oils.Copyright © 2016 Elsevier Ltd and ISBI. All rights reserved.

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