• Neuroimaging Clin. N. Am. · May 2017

    Review

    Radiologically Isolated Syndrome: MR Imaging Features Suggestive of Multiple Sclerosis Prior to First Symptom Onset.

    • Darin T Okuda.
    • Neuroinnovation Program, Multiple Sclerosis and Neuroimmunology Imaging Program, Department of Neurology and Neurotherapeutics, Clinical Center for Multiple Sclerosis, University of Texas Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas, TX 75390-8806, USA. Electronic address: darin.okuda@utsouthwestern.edu.
    • Neuroimaging Clin. N. Am. 2017 May 1; 27 (2): 267-275.

    AbstractRemarkable advances in the understanding of the biology of multiple sclerosis have been achieved through the use of conventional and novel MR imaging techniques of the central nervous system. With improvements in access by patients and utilization of MR imaging technology in health care, an increasing number of unanticipated structural anomalies are being appreciated. In certain instances, white matter abnormalities within the brain and spinal cord are discovered in subjects with no prior history of neurologic symptoms supportive of inflammatory demyelinating events.Copyright © 2017 Elsevier Inc. All rights reserved.

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