• Alessandro Riccardi, Beatrice Spinola, Pierangela Minuto, Maria Ghinatti, Grazia Guiddo, Michele Malerba, and Roberto Lerza.
• S.C. Medicina e Chirurgia d'Accettazione e d'Urgenza, Ospedale San Paolo, Savona - ASL N°2 Savonese, Italy. Electronic address: dottriccardi@gmail.com.
• Am J Emerg Med. 2017 Sep 1; 35 (9): 1317-1319.

IntroductionThe correlation between chronic direct oral anticoagulants (DOACs) intake and the incidence of intracranial complications after minor head injury (MHI) is still not well defined. This study examined the incidence of complications in patients receiving vitamin K antagonists (VKA) or DOACs observed in the emergency department (ED) for MHI.MethodsTwo hundred twenty-five patients affected by MHI and receiving oral anticoagulants were recorded between January and December 2016, distinguishing those treated with VKA (118) from those receiving DOACs (107). All patients underwent a CT scan and were observed for 24h in the ED. Follow-up was performed up to 1month after the head trauma.ResultsThe rate of intracranial hemorrhage was significantly lower in patients treated with DOACs than in patients treated with VKA. We recorded 2 deaths among the 12 patients who experienced intracranial complications in the VKA group.DiscussionDOACs seem to have a more favorable safety profile than VKA in patients affected by MHI. This observation is important in light of the increasing number of elderly patients who are receiving anticoagulant therapy.Copyright © 2017 Elsevier Inc. All rights reserved.

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