• Pedro Iván González-Camarena, Daniel San-Juan, Irene González-Olhovich, David Rodríguez-Arévalo, David Lozano-Elizondo, Carlos Trenado, and David J Anschel.
• Neuro-Ophthalmology Department, National Institute of Neurology and Neurosurgery, Mexico City, Mexico.
• Acta Ophthalmol. 2017 Mar 1; 95 (2): e138-e143.

PurposeTo describe the dynamic changes of the intraocular pressure (IOP) and intracranial pressure (ICP) with normal or pathological values (intracranial hypertension) in nonglaucomatous neurological patients during lumbar punction (LP).MethodsCase-control study, prospective measurement of tonometry in both groups referred for LP. Intraocular pressure, ICP and translaminar pressure difference (TPD) were compared pre- and post-LP.ResultsThirty-six patients (72 eyes) with mean age of 38.5 (16-64) years and BMI of 26.81 kg/m(2) were analysed. The initial mean ICP was 12.81 (± 6.6) mmHg. The mean TPD before and after the LP was 1.48 mmHg and 0.65 mmHg, respectively. The mean IOP of both eyes decreased to 0.8 mmHg post-LP in patients with pathological ICP (p = 0.0193) and normal ICP (p = 0.006).ConclusionsWe found a statistically significant decrease of the IOP post-LP compared to the pre-LP in both groups, being higher in patients with pathological ICP. There were no significant differences of the IOP in patients with normal versus pathological ICP pre-LP/post-LP; neither was found a correlation between ICP and IOP.© 2016 Acta Ophthalmologica Scandinavica Foundation. Published by John Wiley & Sons Ltd.

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