• Pediatric emergency care · Nov 2019

    Clinical Toxicity of Acute Overdoses With L-Thyroxin in Children.

    • Ayse Betul Ergul, Yasemin Altuner Torun, Mahmut Can Serbetci, Alper Ozcan, and Veysel Nijat Bas.
    • From the Department of Pediatrics, Kayseri Training and Research Hospital, Kayseri.
    • Pediatr Emerg Care. 2019 Nov 1; 35 (11): 787-790.

    ObjectivesL-Thyroxine ingestion is rarely seen in children; here, we report our experience of it. This study describes the clinical characteristics and laboratory findings of acute L-thyroxine ingestion in children.MethodsThis retrospective study enrolled patients treated for L-thyroxine ingestion at Kayseri Teaching Hospital between September 2013 and September 2016. Clinical characteristics and laboratory findings are described. Ethical approval was not obtained because the study was retrospective.ResultsThe incidence of L-thyroxine ingestion was 0.07% to 1.2% per year. There were 14 patients. Twelve patients were asymptomatic, but 2 (14.2%) exhibited tachycardia and hypertension. Thyroid hormone levels were elevated in 3 patients (21.4%). Eleven patients did not require medical treatment (78.4%); 3 did. No serious complication or death was observed.ConclusionsAcute ingestion has a benign course. Serious complications are uncommon but may appear several hours or days after ingestion; therefore, patients with L-thyroxine ingestion should be followed closely for 2 weeks.

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