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Modern rheumatology · Oct 2011
Case ReportsSuccessful treatment of a patient with IgG4-related disease with a paravertebral mass lesion.
- Hideki Nakamura, Keiko Hisatomi, Tomohiro Koga, Akinari Mizokami, Satoshi Yamasaki, Mami Tamai, Tomoki Origuchi, Junji Irie, and Atsushi Kawakami.
- Unit of Translational Medicine, Department of Immunology and Rheumatology, Nagasaki University Graduate School of Biomedical Sciences, 1-7-1 Sakamoto, Nagasaki, Nagasaki, 852-8501, Japan. nhideki@nagasaki-u.ac.jp
- Mod Rheumatol. 2011 Oct 1; 21 (5): 524-7.
AbstractA 68-year-old woman was admitted with bleary eyes and lacrimal gland swelling. A biopsy specimen from a right paravertebral mass lesion detected by computed tomography showed remarkable IgG4-positive plasma cells. Because serum IgG4 was elevated to 3300 mg/dl, IgG4-related disease was diagnosed, with the assistance of fluorodeoxyglucose positron emission tomography (FDG-PET)/computed tomography (CT). Administration of 30 mg of oral prednisolone effectively reduced the lacrimal gland swelling and paravertebral mass volume. Nine months after the initiation of prednisolone, serum IgG4 was reduced to 31.4 mg/dl, and there was norecurrence.
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