• The Ochsner journal · Jan 2015

    Amputation as an Unusual Treatment for Therapy-Resistant Complex Regional Pain Syndrome, Type 1.

    • Babak K Kashy, Alaa A Abd-Elsayed, Ehab Farag, Maria Yared, Roya Vakili, and Wael Ali Sakr Esa.
    • Department of Outcomes Research, Cleveland Clinic, Cleveland, OH.
    • Ochsner J. 2015 Jan 1; 15 (4): 441-2.

    BackgroundComplex regional pain syndrome, type 1 (CRPS-1) causes severe pain that can be resistant to multiple treatment modalities. Amputation as a form of long-term treatment for therapy-resistant CRPS-1 is controversial.Case ReportWe report the case of a 38-year-old man who failed all treatment modalities for CRPS-1, including medication, steroid injections, and spinal cord stimulator implantation. Below-the-knee amputation to relieve intractable foot and ankle pain resulted in a favorable outcome for this patient.ConclusionSelect patients with severe CRPS-1 who are unresponsive to all forms of treatment for pain may benefit from amputation as a last option for relief of suffering. Larger studies are needed to prove the efficacy of amputation.

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