• Stefan Linsler, Gerrit Fischer, Volodymyr Skliarenko, Axel Stadie, and Joachim Oertel.
• Klinik für Neurochirurgie, Universitätsklinikum des Saarlandes, Homburg/Saar, Germany.
• World Neurosurg. 2017 Aug 1; 104: 601-611.

ObjectiveKeyhole approaches are under investigation for skull base tumor surgery. They are expected to have a low complication rate with the same successful resection rate compared with endoscopic endonasal procedures. In this study, we compare our current series of tuberculum sellae meningiomas resected via an endoscopic endonasal or microsurgical supraorbital keyhole approach.MethodsBetween 2011 and 2016, 16 patients were treated using the supraorbital keyhole procedure and 6 patients received an endoscopic endonasal procedure. Both surgical techniques were analyzed and compared concerning complications, surgical radicality, endocrinologic, and ophthalmologic outcome and recurrences in patients' follow-up.ResultsThe 2 different approaches yielded similar rates of gross total resection (endonasal 83% [5 of 6] vs. supraorbital 87% [14 of 16]), near total resection (17% [1 of 6] vs. 13% [2 of 16]), and visual recovery (endonasal 66% [2 of 3] vs. supraorbital 60% [3 of 5]). An extension lateral to the internal carotid artery was noted in 81% (13 of 16) of the supraorbital cases and in none of the endonasal cases. Tumor volume was 14.9 cm3 (±8.2 cm3) for supraorbital tumors versus 2.1 cm3 (±0.8 cm3) for the endonasal approach.ConclusionsBoth approaches provide minimally invasive surgical routes accessing meningiomas of the sellar region. The ideal approach should be tailored to the individual patient considering the tumor anatomy, lateral extension, and the experience of the surgeon with both surgical approaches. We suggest using the supraorbital approach for larger meningiomas of sellar region with far lateral extension or broad vascular encasement.Copyright © 2017 Elsevier Inc. All rights reserved.

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