• Br J Anaesth · May 2017

    Review

    Neural network imaging to characterize brain injury in cardiac procedures: the emerging utility of connectomics.

    • B Indja, J P Fanning, J J Maller, J F Fraser, P G Bannon, M Vallely, and S M Grieve.
    • Sydney Translational Imaging Laboratory, Heart Research Institute, Charles Perkins Centre, The University of Sydney, NSW, Australia.
    • Br J Anaesth. 2017 May 1; 118 (5): 680-688.

    AbstractCognitive dysfunction is a poorly understood but potentially devastating complication of cardiac surgery. Clinically meaningful assessment of cognitive changes after surgery is problematic because of the absence of a means to obtain reproducible, objective, and quantitative measures of the neural disturbances that cause altered brain function. By using both structural and functional connectivity magnetic resonance imaging data to construct a map of the inter-regional connections within the brain, connectomics has the potential to increase the specificity and sensitivity of perioperative neurological assessment, permitting rational individualized assessment and improvement of surgical techniques.© The Author 2017. Published by Oxford University Press on behalf of the British Journal of Anaesthesia. All rights reserved. For Permissions, please email: journals.permissions@oup.com.

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