• Eske Kvanner Aasvang, Christoffer Calov Jørgensen, Mogens Berg Laursen, Jacob Madsen, Søren Solgaard, Mogens Krøigaard, Per Kjærsgaard-Andersen, Hans Mandøe, Torben Bæk Hansen, Jørgen Ulrich Nielsen, Niels Krarup, Annette Elisabeth Skøtt, and Henrik Kehlet.
• From the Lundbeck Foundation Centre for Fast-Track Hip and Knee Replacement, Copenhagen University Hospital, Rigshospitalet, Copenhagen (E.K.A., C.C.J., M.B.L., J.M., S.S., M.K., P.K.-A., H.M., T.B.H., J.U.N., N.K., A.E.S., H.K.); Section for Surgical Pathophysiology, Copenhagen University Hospital, Rigshospitalet, Copenhagen (E.K.A., C.C.J., H.K.); Department of Orthopedic Surgery, Aalborg University Hospital, Farsø (M.B.L.); Department of Anesthesia and Intensive Care, Aalborg University Hospital, Farsø (J.M.); Department of Orthopedic Surgery, Copenhagen University Hospital Gentofte, Hellerup (S.S.); Department of Anesthesia and Intensive Care, Copenhagen University Hospital Gentofte, Hellerup (M.K.); Department of Orthopedic Surgery (P.K.-A.), and Department of Anesthesia and Intensive Care (H.M.), Vejle Hospital, Vejle; Department of Orthopedic Surgery, Holstebro Regional Hospital, Holstebro (T.B.H.); Department of Anesthesia and Intensive Care, Holstebro Regional Hospital, Holstebro (J.U.N.); Department of Orthopedic Surgery (N.K.), and Department of Anesthesia and Intensive Care (A.E.S.), Viborg Regional Hospital, Viborg, Denmark.
• Anesthesiology. 2017 Jun 1; 126 (6): 1043-1052.

BackgroundPostanesthesia care unit (PACU) discharge without observation of lower limb motor function after spinal anesthesia has been suggested to significantly reduce PACU stay and enhance resource optimization and early rehabilitation but without enough data to allow clinical recommendations.MethodsA multicenter, semiblinded, noninferiority randomized controlled trial of discharge from the PACU with or without assessment of lower limb motor function after elective total hip or knee arthroplasty under spinal anesthesia was undertaken. The primary outcome was frequency of a successful fast-track course (length of stay 4 days or less and no 30-day readmission). Noninferiority would be declared if the odds ratio (OR) for a successful fast-track course was no worse for those patients receiving no motor function assessment versus those patients receiving motor function assessment by OR = 0.68.ResultsA total of 1,359 patients (98.8% follow-up) were available for analysis (93% American Society of Anesthesiologists class 1 to 2). The primary outcome occurred in 92.2% and 92.0%, corresponding to no motor function assessment being noninferior to motor function assessment with OR 0.97 (95% CI, 0.70 to 1.35). Adverse events in the ward during the first 24 h occurred in 5.8% versus 7.4% with or without motor function assessment, respectively (OR, 0.77; 95% CI, 0.5 to 1.19, P = 0.24).ConclusionsPACU discharge without assessment of lower limb motor function after spinal anesthesia for total hip or knee arthroplasty was noninferior to motor function assessment in achieving length of stay 4 days or less or 30-day readmissions. Because a nonsignificant tendency toward increased adverse events during the first 24 h in the ward was discovered, further safety data are needed in patients without assessment of lower limb motor function before PACU discharge.

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