• Jian Song, Hong-Li Wang, Chao-Jun Zheng, and Jian-Yuan Jiang.
• Department of Orthopaedics, Huashan Hospital, Fudan University, Shanghai, China.
• World Neurosurg. 2017 Sep 1; 105: 69-77.

ObjectiveTo explore risk factors affecting surgical results of Hirayama disease.MethodsA retrospective analysis of 210 patients was performed to identify risk factors affecting surgical results of Hirayama disease by using univariate and multivariate analyses. A receiver operating characteristic curve and area under the curve were applied to evaluate the significant results of the multivariate analysis and the optimal reference value.ResultsThe mean follow-up period was 27.3 months (range, 14-45 months), and 194 patients with clinical and radiographic data completed the final follow-up. Multivariate analysis identified age of patients (cutoff value 22.5 years), duration of the disease (cutoff value 33 months), physiologic reflex, and pathologic reflex as independent risk factors for surgical results of Hirayama disease. The receiver operating characteristic curve analysis and area under the curve showed that good reference value was obtained for the risk factors.ConclusionsAge of patient, duration of the disease, physiologic reflex, and pathologic reflex are the main risk factors affecting surgical results of Hirayama disease. Receiver operating characteristic analysis shows that good reference value was obtained for the risk factors.Copyright © 2017 Elsevier Inc. All rights reserved.

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