• Health affairs · Mar 2008

    Controlled Clinical Trial

    Benefits and costs of immunizing children against influenza at school: an economic analysis based on a large-cluster controlled clinical trial.

    • Jordana Schmier, Su Li, James C King, Kristin Nichol, and Parthiv J Mahadevia.
    • MedImmune Inc. in Gaithersburg, Maryland, USA. mahadeviap@medimmune.com
    • Health Aff (Millwood). 2008 Mar 1; 27 (2): w96-104.

    AbstractCurrent influenza vaccination recommendations focus on immunizing high-risk people; however, influenza mortality and morbidity remain elevated. U.S. policymakers are considering expansion of flu vaccination recommendations to include school-age children (ages 5-18). Children are at risk for flu and propagate epidemic spread. Immunizing children at school offers an efficient approach to covering this population. This study examines the cost consequences of a large multistate, school-based influenza immunization program. The results show that immunization reduces disease among children and adults and is cost-saving to society. An epidemiologically based influenza immunization policy might be an important supplement to the existing risk-based policy.

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