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Critical care clinics · Jul 2017
ReviewAcute Brain Failure: Pathophysiology, Diagnosis, Management, and Sequelae of Delirium.
- José R Maldonado.
- Psychosomatic Medicine Service, Emergency Psychiatry Service, Department of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, 401 Quarry Road, Suite 2317, Stanford, CA 94305-5718, USA. Electronic address: jrm@stanford.edu.
- Crit Care Clin. 2017 Jul 1; 33 (3): 461-519.
AbstractDelirium is the most common psychiatric syndrome found in the general hospital setting, with an incidence as high as 87% in the acute care setting. Delirium is a neurobehavioral syndrome caused by the transient disruption of normal neuronal activity secondary to systemic disturbances. The development of delirium is associated with increased morbidity, mortality, cost of care, hospital-acquired complications, placement in specialized intermediate and long-term care facilities, slower rate of recovery, poor functional and cognitive recovery, decreased quality of life, and prolonged hospital stays. This article discusses the epidemiology, known etiological factors, presentation and characteristics, prevention, management, and impact of delirium.Copyright © 2017 Elsevier Inc. All rights reserved.
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