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Case Reports
Treatment of status epilepticus with plasmapheresis in a patient with thrombotic thrombocytopenic purpura.
- Oktay Bilgir, Ferda Bilgir, Mehmet Calan, Levent Kebapcilar, Baris Pamuk, and Arif Yuksel.
- Department of 2nd Internal Medicine, Izmir Bozyaka Training and Research Hospital, Izmir, Turkey. obilgir2001@yahoo.com
- Transfus Apher Sci. 2011 Oct 1; 45 (2): 149-50.
AbstractThrombotic thrombocytopenic purpura (TTP) is a syndrome with numerous neurological manifestations including altered mental status and seizures. However, status epilepticus (SE) has rarely been reported in this condition. Signs may be transient or fluctuate; however, permanent deficits do occur. Its prognosis was once considered uniformly poor, with a high mortality rate. Since the introduction of plasma infusions and exchanges, the prognosis of the disease has improved dramatically; remissions now occur in 80-90% of patients. Altered mental status in TTP often resolves with plasmapheresis. Likewise, we successfully treated a patient with thrombotic thrombocytopenic purpura (TTP) with pronounced clinical effects of status epilepticus with plasmapheresis and steroid treatment.Copyright © 2011 Elsevier Ltd. All rights reserved.
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