• Curr Opin Crit Care · Oct 2017

    Review

    The evaluation of critically ill transplant patients with infectious diarrhea.

    • Diana F Florescu.
    • aInfectious Diseases Division, University of Nebraska Medical Center bTransplant Surgery Department, University of Nebraska Medical Center, Omaha, Nebraska, USA.
    • Curr Opin Crit Care. 2017 Oct 1; 23 (5): 364-371.

    Purpose Of ReviewThe review summarizes the epidemiology, risk factors, clinical presentation, diagnosis and management of the most important etiologic agents of infectious diarrhea in critically ill transplant recipients.Recent FindingsDiarrhea, frequently caused by infectious pathogens, can cause significant morbidity and mortality in transplant recipients. Diarrhea can lead to severe dehydration, acute renal failure, medication toxicity, rejection, graft-versus-host disease and impairs patients' quality of life. Opportunistic infectious pathogens can pose significant diagnostic and therapeutic challenges in immunocompromised hosts.SummaryIn transplant recipients, it is vital to differentiate infectious from noninfectious diarrhea to adequately manage their therapeutic approach. Supportive measures and reduction in immunosuppression are essential for the treatment management.

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