• Jpn. J. Infect. Dis. · Jan 2011

    Case Reports

    Fatal necrotizing pneumonia caused by Panton-Valentine leukocidin-producing hospital-acquired Staphylococcus aureus: a case report.

    • Hassanain Al-Talib, Habsah Hasan, Chan Yean Yean, Sami M Al-Ashwal, and Manickam Ravichandran.
    • Department of Medical Microbiology and Parasitology, School of Medical Sciences, Universiti Sains Malaysia, Kelantan, Malaysia. hassanainiy@yahoo.com
    • Jpn. J. Infect. Dis. 2011 Jan 1; 64 (1): 58-60.

    AbstractPanton-Valentine leukocidin (PVL) is a cytotoxin which causes leukocyte destruction and tissue necrosis. Although it is produced by fewer than 5% of Staphylococcus aureus strains, PVL-producing S. aureus is emerging as a serious problem worldwide. There has been a marked increase in the incidence of necrotizing lung infections with a very high mortality associated with these strains. This report describes a fatal case of hospital-acquired necrotizing pneumonia caused by PVL-positive methicillin-susceptible S. aureus in a patient with a brain tumor.

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