• Samir Jaber, Giacomo Bellani, Lluis Blanch, Alexandre Demoule, Andrés Esteban, Luciano Gattinoni, Claude Guérin, Nicholas Hill, John G Laffey, Salvatore Maurizio Maggiore, Jordi Mancebo, Paul H Mayo, Jarrod M Mosier, Paolo Navalesi, Michael Quintel, Jean Louis Vincent, and John J Marini.
• Department of Anesthesiology and Critical Care Medicine B (DAR B), Saint-Eloi Hospital, University Teaching Hospital of Montpellier, INSERM U104680, avenue Augustin Fliche, 34295, Montpellier, France. s-jaber@chu-montpellier.fr.
• Intensive Care Med. 2017 Sep 1; 43 (9): 1352-1365.

AbstractIn an important sense, support of the respiratory system has been a defining characteristic of intensive care since its inception. The pace of basic and clinical research in this field has escalated over the past two decades, resulting in palpable improvement at the bedside as measured by both efficacy and outcome. As in all medical research, however, novel ideas built upon observations are continually proposed, tested, and either retained or discarded on the basis of the persuasiveness of the evidence. What follows are concise descriptions of the current standards of management practice in respiratory support, the areas of present-day uncertainty, and our suggested agenda for the near future of research aimed at testing current assumptions, probing uncertainties, and solidifying the foundation on which to base our progress to the next level.

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