• Curr Pain Headache Rep · Dec 2001

    Review

    Analgesic/abortive overuse and misuse in chronic daily headache.

    • H C Diener and Z Katasarva.
    • Department of Neurology, University Essen, Hufelandstr. 55, Essen 45122, Germany. h.diener@uni-essen.de
    • Curr Pain Headache Rep. 2001 Dec 1; 5 (6): 545-50.

    AbstractThe frequent use (> 15 times/month) of medication for the treatment of acute migraine attacks may cause medication overuse headache. This kind of headache can be caused by the intake of combination analgesics, opioids, ergot alkaloids, and triptans. The delay between first intake and daily headache is shortest for triptans (1 to 2 years), longer for ergots (3 years), and longest for analgesics (5 years). Treatment includes drug withdrawal followed by structured acute therapy and initiation of migraine prophylactic treatment.

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