• J. Child Neurol. · Jul 2015

    Factors Associated With Increased In-Hospital Mortality Among Children With Intracerebral Hemorrhage.

    • Malik M Adil, Adnan I Qureshi, Lauren A Beslow, Ahmed A Malik, and Lori C Jordan.
    • Department of Internal Medicine and Neurology, Ochsner Neuroscience Institute, Ochsner Clinic Foundation, New Orleans, LA, USA Zeenat Qureshi Stroke Institute, St Cloud, MN, USA malikmuhammad.adil@gmail.com.
    • J. Child Neurol. 2015 Jul 1; 30 (8): 1024-8.

    AbstractWe assessed factors associated with mortality and potential targets for intervention in a large national sample of children with nontraumatic intracerebral hemorrhage. Using Healthcare Cost and Utilization Project Kids' Inpatient Database ICD-9-CM code 431 identified children aged 1 to 18 years with nontraumatic intracerebral hemorrhage in 2003, 2006 and 2009. Intracerebral hemorrhage was the primary diagnosis for 1172 children (ages 1-18 years) over the 3-year sample. Factors associated with mortality based on multivariable logistic regression included Hispanic ethnicity (odds ratio 1.9, 95% confidence interval 1.1-3.3), older age (11-18 vs 1-10 years, odds ratio 2.5, 95% confidence interval 1.3-5.0), coagulopathy (odds ratio 3.0, 95% confidence interval 1.6-6.0), and coma (odds ratio 9.0, 95% confidence interval 3.2-24.6). From 2003 to 2009, there was a non-significant decrease in mortality with a significant increase in length of stay from 9 to 11 days (P < .003). In children with intracerebral hemorrhage, coma and coagulopathy had the strongest association with mortality; coagulopathy is a potentially modifiable risk factor.© The Author(s) 2014.

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