• Lancet · Aug 2017

    Review

    Update on antithrombotic therapy after percutaneous coronary revascularisation.

    • Thomas Cuisset, Verheugt Freek W A FWA Department of Cardiology, Onze Lieve Vrouwe Gasthuis, Amsterdam, Netherlands., and Laura Mauri.
    • Département de Cardiologie, CHU Timone, Marseille, France; Aix-Marseille Université, Faculté de Médecine, Marseille, France. Electronic address: thomas.cuisset@ap-hm.fr.
    • Lancet. 2017 Aug 19; 390 (10096): 810-820.

    AbstractFor relief of coronary obstruction, percutaneous coronary intervention has become a standard-of-care procedure over the past 40 years. Nonetheless, optimal outcomes after coronary stenting require careful attention to antithrombotic therapy. This review aims to summarise the current available evidence and discusses how to integrate scientific knowledge into clinical decisions. In recent years, improvement and modifications of drugs and devices have changed the field tremendously, and substantially benefitted patient outcomes. The key challenge of how to provide optimal protection against thrombotic events without excessive increases in bleeding risk has remained the same for decades. Alternative strategies with new drugs, both antiplatelet and anticoagulant agents, and new coronary stents will continue the journey to achieve this ultimate goal.Copyright © 2017 Elsevier Ltd. All rights reserved.

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