• Epilepsy research · Jun 2012

    Review

    Reflex seizures and reflex epilepsies: old models for understanding mechanisms of epileptogenesis.

    • Salvatore Striano, Antonietta Coppola, Luigi del Gaudio, and Pasquale Striano.
    • Epilepsy Centre, Department of Neurological Sciences, Federico II University, Napoli, Italy. sstriano@libero.it
    • Epilepsy Res. 2012 Jun 1; 100 (1-2): 1-11.

    AbstractReflex seizures and epilepsies represent an ancient human model to understand basic mechanisms of epilepsy. The increase of light stimulation makes this issue extremely actual and interesting. In addition, a lot of observations show the frequent occurrence of provoked seizures in malformations of cortical development and in recently defined conditions such as familial or sporadic lateral temporal epilepsy. Advances in morphological and functional neuroimaging techniques, and the possibility of their fusion with EEG (e.g., fMRI-EEG co-registration) offer a unique non-invasive opportunity to investigate cortical areas and brain networks involved in cerebral functions and in epileptic discharges.Copyright © 2012 Elsevier B.V. All rights reserved.

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