• Mihai Dorin Vartolomei, Bernhard Kiss, Alvaro Vidal, Fiona Burkhard, George N Thalmann, and Beat Roth.
• Department of Urology, University of Bern, Bern, Switzerland.
• BJU Int. 2016 Apr 1; 117 (4): 618-28.

ObjectiveTo evaluate the long-term oncological and functional outcomes of re-adaptation of the dorsolateral peritoneal layer after pelvic lymph node dissection (PLND) and cystectomy.Patients And MethodsA randomized, single-centre, single-blinded, two-arm trial was conducted on 200 consecutive patients who underwent PLND and cystectomy for bladder cancer (ResultsThere was no significant difference between the two groups in terms of the rate of local (pelvic) recurrence (5/95 [5.3%] in group A; 7/93 [7.5%] in group B; P = 0.53), the rate of distant metastases (21/95 [22.1%] in group A; 23/93 [24.7%] in group B; P = 0.67), cancer-specific survival (P = 0.37) or overall survival (P = 0.59). Group A had significantly better bowel function at 3 (P < 0.001), 6 (P < 0.006), 12 (P < 0.006) and 24 months (P = 0.04), and significantly less postoperative abdominal pain and bloating at 3 (P = 0.002) and 6 months (P = 0.01).ConclusionRe-adaptation of the dorsolateral peritoneal layer after PLND and cystectomy has a beneficial long-term impact on bowel function and postoperative pain without compromising oncological radicality.© 2015 The Authors BJU International © 2015 BJU International Published by John Wiley & Sons Ltd.

39 keywords...

hide…