• Takeo Anda, Masahiro Yonekura, Hiroshi Baba, Kazuhiko Suyama, Keisuke Toda, Kensaku Kamada, Tomonori Ono, Koichi Yoshida, Shiro Baba, and Masanari Onizuka.
• Department of Neurosurgery, National Nagasaki Medical Center, Nagasaki, Japan. me130@sunny.ocn.ne.jp
• Neurol. Res. 2006 Mar 1; 28 (2): 165-71.

Background And PurposeSeveral unruptured cerebral aneurysms have been reported to grow and rupture. To determine which factors affect the growth of these aneurysms during the acute stage of subarachnoid hemorrhage (SAH), a retrospective review was performed.MethodsBetween January 2000 and January 2003, 130 patients with angiographically proven ruptured cerebral aneurysms were treated at our institution. Of these patients, 32 also had simultaneous unruptured aneurysms, and the total number of the unruptured aneurysms was 40, including two neck remnants which had remained since the past clipping. Seventeen patients had 17 unruptured aneurysms and two neck remnants. The unruptured aneurysms were not treated during the acute stage of SAH but had received a complete short term follow-up.ResultsThe rapid growth of one unruptured aneurysm and two neck remnants was confirmed by a second angiogram performed on average 40 days after the first angiogram. Several candidate factors responsible for the growth of aneurysm were selected, and the results of a statistical analysis indicate that a systolic blood pressure above 200 mmHg during the acute stage of SAH and vasospasm, confirmed by transcranial Doppler ultrasound (TCD) or neurological examination, and neck remnants, are risk factors that affect the growth.ConclusionsShort term follow-up angiography is thus important for patients with untreated unruptured cerebral aneurysms after the acute stage of SAH.

39 keywords...

hide…